Mimighoul is an EARTH attribute flip archetype who's effects revolve around setting themselves to your opponent's field and subsequently flipping them up with other effects, such as that of Mimighoul Master, that negatively affect your opponent and benefit you, before returning themselves to your field face up, allowing you to make xyz or link plays.
A basic one card combo would be:
Start with Mimighoul Dragon in hand, normal summon it and activate it's effect, grabbing you a Mimighoul Maker.
Activate maker, revealing Mimighoul Archfiend and Mimighoul Slime. One is randomly put face down to your opponents field.
If you got archfiend in hand, summon it using the effect of maker and activate archfiends effect to flip up the face down slime, allowing you to special summon a mimighoul from deck. The best approach here would be to summon Mimighoul Maker and search fairy, then xyz into Giant mimighoul and search dungeon, adding any mimighoul, before either special summoning fairy from hand and link summoning using Giant and fairy, or just leaving the Maker and Giant on the board.
If you got slime in hand, special summon it through makers effect and then xyz summon Giant Mimighoul and fetch a Mimighoul Dungeon from deck and activate it, then use its effect to search any mimighoul, except Master. From there, set the mimighoul top your opponents field face down and pass turn. Because of Mimighoul dungeons effect, they must flip up your monster or they cannot normal summon, where you will benefit. If the choose not to do this and instead special summon immediately, you can banish Maker from grave on summon to flip up the monster anyway.
The reason i run summoning curse and reverse reuse is that, in summoning curses case, every time you summon a mimighoul to their field, your opponent must banish a card from their hand as they control that monster. In reverse reuse's case, i use it as basically 2 more mimighoul room's, as it allows you to set flip monsters from your grave to your opponents field, allowing you to lock your opponent out of normal summoning while reusing link materials to put on your opponents field.
Kashtira also works very well in this deck as the mimighouls activating on your opponents field allows you to banish a card from the ED, same with Talents effects.